It's a high profile day for Seattle Grace, high profile names become staff and high profile cases arrive, specifically the arrival of Dr. Addison Forbes Montgomery-Shepherd and the mother of quintuplets, in which three of the five are surgical cases. Meanwhile, the rest of the interns face their own low profile dilemmas, as Meredith's one night stand shows up at the hospital more than pleased to see her, Cristina gets keyed and Alex makes a major mistake, both professionally and romantically.