In this week’s episode, sponsored by Regeneron and Sanofi Genzyme, we spoke with Dr. Ezra Cohen from UC San Diego Health, as well as two patients with advanced cutaneous squamous cell carcinoma. To start, Cohen helped us to understand how common the disease is and what treatment options are available for patients. We also spoke with Josh, who was diagnosed in 2017 after having a spot on his forehead removed using MOH’s surgery. However, the growth returned, and after a second opinion in 2019, he was referred to The University of Texas MD Anderson Cancer Center in Houston. Following his experience, Josh offered advice for other patients with advanced cutaneous squamous cell carcinoma. Lastly, we talked to Bud, who was diagnosed previously with basal cell carcinoma and has also received a diagnosis of advanced cutaneous squamous cell carcinoma. He now gets radiation and immunotherapy to treat his cancer and hopes that other patients will learn about their disease in order to advocate for themselves.