In this episode we have a conversation with Patrick Bradshaw about issues related to measurement error, misclassification, and information bias. We ask him to help define and clarify the differences between these concepts. We chat about dependent and differential forms of misclassification and how helpful DAGs can be for identifying these sources of bias. Patrick helps to explain the problem with the over-reliance on non-differential bias producing a bias toward the null and concerns about being “anchored to the null” in epidemiologic analyses. This episode will also serve to provide you with the most up-to-date information from Patrick on his recommendations about excellent new TV shows to stream (Wednesday on Netflix; Wandavision on Disney+). Two thumbs up.