Science with The Blunt Letters

S5 Ep 15: Ergot Poisoning - Hallucinations and History


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In the second installment of The Blunt Letters Poisoning Series, Elle and Micaela dive into the strange and terrifying history of ergot poisoning. From contaminated rye bread in the Middle Ages to its possible connection with the Salem Witch Trials, ergot has been haunting humanity for centuries. We explore the science of the fungus Claviceps purpurea, how it causes convulsions, hallucinations, and gangrene, and why it earned the nickname “St. Anthony’s Fire.” Plus, we discuss ergot’s surprising role in the discovery of LSD and its lasting impact on medicine, mysticism, and culture. Join us for a mix of history, toxicology, and true crime science in this deep dive into one of the world’s most notorious natural poisons.


Featuring Original Song "Who Farted?" by Micaela Superstar


References:

Ergot ErgotismLSDHow Rye Bread May Have Caused the Salem Witch Trials

Ergotism Today

Ergot: from witchcraft to biotechnology 

Were They Bitten? Or is it Ergot Poisoning?

CIA sued over 1950s 'murder' of government scientist plied with LSD

MK ultra wiki


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