Ginseng and goldenseal are widely known and used for their purported medicinal properties. Galax is a native plant harvested for use in flower arrangements. White oak is used in traditional Cherokee basket weaving. The Southern Appalachians are home to a botanical bounty of wild plants that have found plenty of human uses. In many cases, behind those uses is a market where these plants are bought and sold, usually legally, sometimes not so. A great challenge for all involved in the legal trade of these plants is ensuring they are properly managed and sustainably harvested.