This episode delves into sarcoidosis, a complex chronic granulomatous disease that primarily affects the lungs, lymph nodes, and skin. We discuss the hallmark non-caseating granulomas, symptoms like dry cough, fatigue, and erythema nodosum, and highlight the ‘GRUELING’ mnemonic to remember key systemic manifestations. With insights into diagnostic tools such as CXR, pulmonary function tests, and histology, we explore how sarcoidosis is a diagnosis of exclusion. Tune in for an in-depth look at long-term management, including corticosteroids and methotrexate, and the importance of a multidisciplinary approach for improved patient outcomes. This is a medical education podcast episode for medical students.