Saving The American Chestnut: A Case Study, we explore more deeply the complicated question of using biotechnology to make forests more resistant to climate change. We look to the story of the American Chestnut as an example of how scientists are trying to bring a once-abundant tree back from near extinction through genetic engineering. We also consider the budding genome-editing technology CRISPR Cas-9 as a more precise tool with great promise but also great uncertainty. Can we do it and should we do it?