Brian Jacobs, MD, project director of Integrating Clinical Information Systems, or ICIS, at Cincinnati Children's Hospital Medical Center, discusses how efforts in computerized physician order entry relate to patient safety. The ICIS system is a computer-based system implemented Thuoughout the hospital Thuough which all medical orders are entered and documented electronically. The system, believed to be the most comprehensive in any pediatric hospital in the United States, is expected to reduce medical errors significantly.