After decades of mystery, Gladstone researchers identify a gene that can derail heart formation—and show that fixing it prevents the problem in mice.This is an audio version of the article, <a href='https://gladstone.org/news/scientists-pinpoint-key-gene-behind-heart-defects-down-syndrome'>"Scientists Pinpoint a Key Gene Behind Heart Defects in Down Syndrome,"</a> published on Gladstone.org.  <ul><li><a href='https://gladstone.org/news/scientists-pinpoint-key-gene-behind-heart-defects-down-syndrome'>Read the article on our website</a>.</li><li><a href='https://www.nature.com/articles/s41586-025-09593-9'>Read the scientific publication.</a></li></ul>

After decades of mystery, Gladstone researchers identify a gene that can derail heart formation—and show that fixing it prevents the problem in mice. This is an audio version of the article, "Scientists Pinpoint a Key Gene Behind Heart Defects in Down Syndrome," published on Gladstone.org. Read the article on our website.Read the scientific publication.

After decades of mystery, Gladstone researchers identify a gene that can derail heart formation—and show that fixing it prevents the problem in mice.This is an audio version of the article, <a href="https://gladstone.org/news/scientists-pinpoint-key-gene-behind-heart-defects-down-syndrome" rel="noopener noreferrer">"Scientists Pinpoint a Key Gene Behind Heart Defects in Down Syndrome,"</a> published on Gladstone.org. &nbsp;<ul><li><a href="https://gladstone.org/news/scientists-pinpoint-key-gene-behind-heart-defects-down-syndrome" rel="noopener noreferrer">Read the article on our website</a>.</li><li><a href="https://www.nature.com/articles/s41586-025-09593-9" rel="noopener noreferrer">Read the scientific publication.</a></li></ul>

Scientists Pinpoint a Key Gene Behind Heart Defects in Down Syndrome

Transform your commute or downtime into an opportunity to stay informed with the latest scientific breakthroughs and stories happening at Gladstone Institutes. This isn't your typical podcast—it's your favorite Gladstone articles brought to life through high-quality audio narration, delivered directly to your preferred podcast platform. Each episode features AI-narrated versions of stories from Gladstone's newsroom, allowing you to stay connected to the news that matters most without being tied to a screen. Gladstone Audio News brings you the same compelling storytelling you expect from Gladstone—just in audio form. Subscribe today and never miss a story. New episodes published regularly featuring the latest stories from Gladstone's editorial team.

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Transform your commute or downtime into an opportunity to stay informed with the latest scientific breakthroughs and stories happening at Gladstone Institutes. This isn't your typical podcast—it's your favorite Gladstone articles brought to life through high-quality audio narration, delivered directly to your preferred podcast platform. Each episode features AI-narrated versions of stories from Gladstone's newsroom, allowing you to stay connected to the news that matters most without being tied to a screen. Gladstone Audio News brings you the same compelling storytelling you expect from Gladstone—just in audio form. Subscribe today and never miss a story. New episodes published regularly featuring the latest stories from Gladstone's editorial team.

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Scientists Pinpoint a Key Gene Behind Heart Defects in Down Syndrome

Scientists Pinpoint a Key Gene Behind Heart Defects in Down Syndrome