Light O'Clock

Season 2 – Episode 2: Sleep and circadian rhythms – same or different?


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In today’s episode, we dive deep into the relationship between circadian rhythms and the sleep-wake cycle with Dr. Renske Lok from Stanford University. Are they different or the same? What other processes in the body regulate your sleep? Can you catch-up on lost sleep? How can you even know if you are sleep-deprived and need more sleep? Tune in to get the answers to these and many other questions on sleep and circadian rhythms.

Links and resources related to the episode’s content
  • Graphic of sleep pressure (process S) and circadian rhythms (process C) [https://static.physoc.org/app/uploads/2019/03/22194528/Fig3.jpg]

  • Further reading on the two-process model of sleep [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540767/]

  • Disconnect between how sleepy people feel (subjective) and how sleepy they actually are (objective) [https://doi.org/10.2147/NSS.S312808]

  • Timestamps

    (00:00) Intro

    (02:08) Introducing Dr. Lok
    (02:44) Circadian rhythms: from morning to night
    (06:37) Sleep and circadian rhythms: same or different?
    (08:10) The two-process model of sleep
    (09:08) The “forbidden” zone
    (10:02) Travel and jet-lag
    (11:35) How does sleep pressure work?
    (14:28) Can you catch-up on lost sleep?
    (17:19) How to know if you’re sleep-deprived?
    (20:03) Separating process S and C in the lab
    (26:20) Outro

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    Light O'ClockBy Translational Sensory & Circadian Neuroscience Unit (MPS/TUM/TUMCREATE)