“Zombie cells” aren’t a meme—senescent cells accumulate with age, pump out inflammatory signals (SASP), and can sabotage joints, lungs, vessels, brain health, and recovery. In this episode of The Human 5.0 Project, Ultimate Biohacker 10X breaks down the real science of senolytics: where the concept came from, what senescent cells actually do, how senolytics work (and why dosing in trials is pulsed), and what the human evidence looks like so far.

We cover:

What senescent cells are + why they accumulate (Hayflick limit → modern aging biology) ScienceDirect

SASP: the inflammatory “broadcast” that damages nearby tissue PMC

How the first senolytics (Dasatinib + Quercetin) were discovered and tested PMC+1

What human studies/trials have actually reported (including feasibility/safety-focused work) ScienceDirect+1

Why measurement is hard: senescence biomarkers aren’t one simple blood test Cell

Medical disclaimer: This content is educational only—not medical advice. Senolytics include prescription drugs and investigational therapies with real risks and unknown long-term outcomes. Do not self-experiment; talk to a qualified clinician.

Please subscribe for free to The Human 5.0 Project.

For more longevity insights and protocols, check out biohackerdepot.com – your go-to resource for cutting-edge health optimization strategies.

And if you're sourcing research peptides , peptidesphere.com has a curated selection of peptides and bioregulators with detailed info on quality and applications.

#Senolytics #ZombieCells #CellularSenescence #SASP #Longevity #Healthspan #AntiAging2026 #Biohacking #Inflammation #Frailty #HealthyAging #Mitochondria #Autophagy #Quercetin #Fisetin #Dasatinib #ScienceBased #Human50Project #UltimateBiohacker10X #RegenerativeMedicine