This episode is focused on sepsis. I also talk about the relevance of the glycocalyx. And emphasise how much extrapolation there is from human medicine to veterinary practice.

Topics covered include:

• Long-standing sepsis definitions and recently suggested updates
• History of sepsis management in human medicine; including early-goal directed therapy and Surviving Sepsis Campaign
• Recent large scale human trials: ProCESS (USA), ARISE (Australasia), ProMISe (UK)
• Key steps for managing the septic veterinary patient
• The glycocalyx: what it is, what it does, why it is relevant, implications for practice

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