JACI: In Practice Deputy Editor Scott Sicherer describes the September 2021 issue, the theme of which is “Eosinophilic Gastrointestinal Diseases.” Theme topics covered include various aspects of eosinophilic esophagitis, including the role of the environment and treatment, as well as clinicopathologic correlations and emerging therapies in eosinophilic gastrointestinal disease. Dr. Sicherer then presents the Highlights of the Original Articles in the issue, which are on the topics of Eosinophilic gastrointestinal diseases. COVID-19, Asthma, Atopic triad, Cough, Drug Allergy, Food Allergy, and Immunodeficiency. Read the issue: https://bit.ly/JAIPSept2021. Access JACI: In Practice’s entire library: https://www.jaci-inpractice.org