JACI: In Practice Editor Michael Schatz describes the September issue, the theme of which is “Biologics”. Theme topics covered include the use of biologics for asthma, chronic rhinosinusitis with nasal polyps, eosinophilic esophagitis, and hypereosinophilic syndromes. Dr. Schatz then presents the Highlights of the Original Articles in the issue, which are on the topics of Biologics, Asthma, Dermatitis, Drug Allergy, Eosinophilic Disorders, Food Allergy, Immunodeficiency, Immunotherapy, Insect Sting Allergy, and Urticaria.