This sermon explores Romans 12:12, emphasizing God's prescription for perseverance during trials. Pastor Ben Jacquot explains how rejoicing in hope, being patient in tribulation, and being constant in prayer are interconnected commands that form God's plan for believers to endure difficulties. He highlights that these commands are not only prescribed by God but also provided for in the gospel and modeled by Jesus Christ. The sermon emphasizes the importance of setting one's mind on future glory and maintaining contentment in God's plan while experiencing pain.