Sepsis is one of the most common and deadly emergencies you’ll encounter on boards and in clinical practice. In this episode of One Stem at a Time, we break down sepsis from start to finish: what it is, how the body responds, and when it turns into septic shock. Learn the key mechanisms behind systemic inflammation, the classic clinical clues that signal organ dysfunction, and the stepwise management strategy that saves lives. By the end of this episode, you’ll be able to recognize sepsis, understand its pathophysiology, and recall the high-yield treatment priorities that boards love. Perfect for rapid review and clinical reasoning reinforcement.

High-Yield Takeaways Include:

• Understanding the dysregulated host response to infection

• Differentiating sepsis from septic shock

• Prioritizing time-critical interventions: fluids, antibiotics, vasopressors, and source control