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Short Shorts: 3rd Week March 2022
Vidcast: https://youtu.be/cnN2nkBlDec
Short Shorts are cutting edge medical and healthcare discoveries not quite ready for the clinic, but worth knowing about now.
Spiders may help us cure cancer. The intracellular protein p53 is one natural defense against cancer-triggering mutations. Problem is that p53 is in short supply since cells naturally make very little of it and it tends to be unstable. That’s where our creepy spider friends come in. Tumor biologists at Sweden’s Karolinska Institute find that a small section of synthetic spider silk protein attached to p53 before reintroducing it into cells stabilizes the p53 enhancing its ability to prevent cancer-causing mutations. Could be the basis for a new treatment.
https://www.cell.com/structure/fulltext/S0969-2126(22)00049-1?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0969212622000491%3Fshowall%3Dtrue
A new type of CoVid vaccine repurposes red blood cells to carry the viral spike proteins that trigger a effective immune protection. A team at Canada’s McMaster University starts with normal red blood cells, RBCs for short, empties their insides, and then attaches spike proteins to the remaining cell membranes. These modified RBCs can carry an abundance of different spike proteins permitting vaccination and boosting against many variants.
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0263671
We know that indoor air filtration is an essential tool in our battle against CoVid. Now the UK’s University of Birmingham has developed antimicrobial air filters that combine the high air flow filters with the germicide chlorhexidine digluconate. This hybrid system can kill CoVid virus in the air passing through it while treating a high volume of room air.
https://www.nature.com/articles/s41598-022-06579-9
In an effort to better understand the forces that create concussive brain injuries in athletes, UK engineers have developed a high tech mouthguard equipped with accelerometers and triaxial gyroscopes that can gather data capable of measuring impact velocities. Hopefully this type of wearable can better help prevent CTE, chronic traumatic encephalopathy, that has plagued professional football players.
https://www.medrxiv.org/content/10.1101/2022.03.02.22271563v1
There you have the latest. When additional information about these developments becomes available, I’ll pass it on to you.
#spiders #p53 #cancer #erythrocytes #CoVid #vaccine #variants #airfiltration #chlorhexidine #mouthguard #wearables #cte
View all episodes
By Howard G. Smith MD, AM
Vidcast: https://youtu.be/cnN2nkBlDec
Short Shorts are cutting edge medical and healthcare discoveries not quite ready for the clinic, but worth knowing about now.
Spiders may help us cure cancer. The intracellular protein p53 is one natural defense against cancer-triggering mutations. Problem is that p53 is in short supply since cells naturally make very little of it and it tends to be unstable. That’s where our creepy spider friends come in. Tumor biologists at Sweden’s Karolinska Institute find that a small section of synthetic spider silk protein attached to p53 before reintroducing it into cells stabilizes the p53 enhancing its ability to prevent cancer-causing mutations. Could be the basis for a new treatment.
https://www.cell.com/structure/fulltext/S0969-2126(22)00049-1?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0969212622000491%3Fshowall%3Dtrue
A new type of CoVid vaccine repurposes red blood cells to carry the viral spike proteins that trigger a effective immune protection. A team at Canada’s McMaster University starts with normal red blood cells, RBCs for short, empties their insides, and then attaches spike proteins to the remaining cell membranes. These modified RBCs can carry an abundance of different spike proteins permitting vaccination and boosting against many variants.
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0263671
We know that indoor air filtration is an essential tool in our battle against CoVid. Now the UK’s University of Birmingham has developed antimicrobial air filters that combine the high air flow filters with the germicide chlorhexidine digluconate. This hybrid system can kill CoVid virus in the air passing through it while treating a high volume of room air.
https://www.nature.com/articles/s41598-022-06579-9
In an effort to better understand the forces that create concussive brain injuries in athletes, UK engineers have developed a high tech mouthguard equipped with accelerometers and triaxial gyroscopes that can gather data capable of measuring impact velocities. Hopefully this type of wearable can better help prevent CTE, chronic traumatic encephalopathy, that has plagued professional football players.
https://www.medrxiv.org/content/10.1101/2022.03.02.22271563v1
There you have the latest. When additional information about these developments becomes available, I’ll pass it on to you.
#spiders #p53 #cancer #erythrocytes #CoVid #vaccine #variants #airfiltration #chlorhexidine #mouthguard #wearables #cte