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Short Shorts: 4th Week March 2022
Vidcast: https://youtu.be/WcL5hqXlq-Q
Short Shorts are cutting edge medical and healthcare discoveries not quite ready for the clinic. They’re worth knowing about now during the 4th week of March, 2022.
The FDA and Pfizer have just issued a flash recall for the blood pressure drug Accuretic, the brand for a quinapril/hydrochlorthazide combo. The drug contains unacceptable levels of a nitrosamine which may be carcinogenic. If you take this drug, call your pharmacy to see if your lot is affected and to get a replacement.
https://content.govdelivery.com/accounts/USFDA/bulletins/31018cd
Hope for an anti-CoVid antibody that capably neutralizes past and future variants and sub-variants is increased by two teams of researchers. One team in Alabama and Texas, and the other in Switzerland, France, and Belgium. Both teams identified antibodies from recovered CoVid patients directed against the a part of the coronavirus spike that rarely varies yet is critical for viral replication. While the usual antibodies are directed against the mutating receptor binding domain at the spike head, these new antibodies are directed against a site on the stalk of the spike that varies little.
https://www.biorxiv.org/content/10.1101/2022.03.05.483133v1
https://www.biorxiv.org/content/10.1101/2022.03.18.484873v1.full.pdf+html
From Canada’s University of Waterloo comes a novel form of MRI imaging that lights up cancerous tissues to differentiate them from normal, healthy tissue. Called synthetic correlated diffusion imaging, it allows cancers to light up because water molecules within cancer cells move differently than they do in normal cells. The technique successfully identified cancerous prostate tumors.
https://www.nature.com/articles/s41598-022-06872-7
CoVid vaccination does not adversely affect the results of IVF. An Israeli study compared 200 vaccinated women with 200 controls and found no differences in the number of eggs retrieved per cycle and fertilization rates. Comparing 128 vaccinated women with 133 untaxed, the pregnancy rates were almost identical at 32.8% vs 33.1%.
https://www.fertstert.org/article/S0015-0282(22)00144-3/pdf
Triple negative breast cancer spreads rapidly, kills many younger women, and is difficult to conquer with usually successful immunotherapy. These cancer cells wipe themselves clean of the antigens the immune system needs to recognize and kill them. Spanish oncologists now show that gene therapy using mRNA turns on production of the so-called LCOR that facilitates tumor antigen expression on the cell surface. This technique opens the door for more effective breast cancer i
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By Howard G. Smith MD, AM
Vidcast: https://youtu.be/WcL5hqXlq-Q
Short Shorts are cutting edge medical and healthcare discoveries not quite ready for the clinic. They’re worth knowing about now during the 4th week of March, 2022.
The FDA and Pfizer have just issued a flash recall for the blood pressure drug Accuretic, the brand for a quinapril/hydrochlorthazide combo. The drug contains unacceptable levels of a nitrosamine which may be carcinogenic. If you take this drug, call your pharmacy to see if your lot is affected and to get a replacement.
https://content.govdelivery.com/accounts/USFDA/bulletins/31018cd
Hope for an anti-CoVid antibody that capably neutralizes past and future variants and sub-variants is increased by two teams of researchers. One team in Alabama and Texas, and the other in Switzerland, France, and Belgium. Both teams identified antibodies from recovered CoVid patients directed against the a part of the coronavirus spike that rarely varies yet is critical for viral replication. While the usual antibodies are directed against the mutating receptor binding domain at the spike head, these new antibodies are directed against a site on the stalk of the spike that varies little.
https://www.biorxiv.org/content/10.1101/2022.03.05.483133v1
https://www.biorxiv.org/content/10.1101/2022.03.18.484873v1.full.pdf+html
From Canada’s University of Waterloo comes a novel form of MRI imaging that lights up cancerous tissues to differentiate them from normal, healthy tissue. Called synthetic correlated diffusion imaging, it allows cancers to light up because water molecules within cancer cells move differently than they do in normal cells. The technique successfully identified cancerous prostate tumors.
https://www.nature.com/articles/s41598-022-06872-7
CoVid vaccination does not adversely affect the results of IVF. An Israeli study compared 200 vaccinated women with 200 controls and found no differences in the number of eggs retrieved per cycle and fertilization rates. Comparing 128 vaccinated women with 133 untaxed, the pregnancy rates were almost identical at 32.8% vs 33.1%.
https://www.fertstert.org/article/S0015-0282(22)00144-3/pdf
Triple negative breast cancer spreads rapidly, kills many younger women, and is difficult to conquer with usually successful immunotherapy. These cancer cells wipe themselves clean of the antigens the immune system needs to recognize and kill them. Spanish oncologists now show that gene therapy using mRNA turns on production of the so-called LCOR that facilitates tumor antigen expression on the cell surface. This technique opens the door for more effective breast cancer i