The "Gluten-Free" movement for those without Celiac Disease was one of the earliest health trends in recent years and remains a very popular dietary option today.  Nearly every grocery store, restaurant, and recipe has gluten-free options.  While a medical necessity for those with Celiac Disease, others voluntarily choose to maintain a gluten-free diet. There has been heavy debate on whether or not there is a health benefit to following a gluten-free diet if you don't have Celiac Disease, which has led to the emergence of the term "Non-Celiac Gluten (Wheat) Sensitivity".  Since headlines and anecdotes muddy the waters on this issue, Andy and Aaron dive into the research to get some answers, as well as share their experience with gluten.

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Resources:

• Jimmy Kimmel - What is Gluten?
• Non-Celiac Gluten Sensitivity: The New Frontier of Gluten Related Disorders [Nutrients 2013]
• Non-Celiac Wheat Sensitivity: Exploring a New Clinical Entity [American Journal of Gastroenterology 2012]
• Effect of Gliadin on Intestinal Permeability [Nutrients 2015]
• Markers of Non-Celiac Wheat Sensitivity in Patients with Chronic Fatigue Syndrome [Gut 2019]
• Intestinal Cell Damage in Individuals Reporting Sensitivity to Wheat in the Absence of Celiac Disease [Gut 2016]
• Serological Tests in Gluten Sensitivity (Nonceliac Gluten Intolerance) [Journal of Clinical Gastroenterology 2012]
• Neurologic and Psychiatric Manifestations of Celiac Disease and Gluten Sensitivity [Psychiatric Quarterly 2012]
• Headache Associated with Celiac Disease: A Systematic Review and Meta-Analysis [Nutrients 2018]
• A survey on patients suspected of having non-celiac gluten sensitivity [BMC Medicine 2014]
• Migraine and Celiac Disease [Journal of Head and Face Pain 2003]
• Extra-intestinal manifestations of non-celiac gluten sensitivity: An expanding paradigm [World Journal of Gastroenterology 2018]
• Anxiety but Not Depression Decreases in Coeliac Patients After One-Year Gluten-Free Diet [Scandinavian Journal of Gastroenterology 2001]
• Dietary Gluten and the Development of Type 1 Diabetes [Diabetologia 2014]
• Gluten Sensitivity: From Gut to Brain [The Lancet Neurology 2010]
• Increased Prevalence and Mortality in Undiagnosed Celiac Disease [Gastroenterology 2009]
• Cyrex Laboratories: Array 3