Many real-world application domains such as sensor-monitoring systems for environmental research or medical diagnostic systems are dealing with data that is represented by multiple

observations. In contrast to single-observation data, where each object is assigned to exactly one occurrence, multi-observation data is based on several occurrences that are subject to two key properties: temporal variability and uncertainty. When defining similarity between data objects, these properties play a significant role. In general, methods designed for single-observation data hardly apply for multi-observation data, as they are either not supported by the data models or do not provide sufficiently efficient or effective solutions.

Prominent directions incorporating the key properties are the fields of time series, where data is created by temporally successive observations, and uncertain data, where observations are mutually exclusive. This thesis provides research contributions for similarity processing - similarity search and data mining - on time series and uncertain data.

The first part of this thesis focuses on similarity processing in time series databases. A variety of similarity measures have recently been proposed that support similarity processing w.r.t. various aspects. In particular, this part deals with time series that consist of periodic occurrences of patterns. Examining an application scenario from the medical domain, a solution for activity recognition is presented. Finally, the extraction of feature vectors allows the application of spatial index structures, which support the acceleration of search and mining tasks resulting in a significant efficiency gain. As feature vectors are potentially of high dimensionality, this part introduces indexing approaches for the high-dimensional space for the full-dimensional case as well as for arbitrary subspaces.

The second part of this thesis focuses on similarity processing in probabilistic databases. The presence of uncertainty is inherent in many applications dealing with data collected by sensing devices. Often, the collected information is noisy or incomplete due to measurement or transmission errors. Furthermore, data may be rendered uncertain due to privacy-preserving issues with the presence of confidential information. This creates a number of challenges in terms of effectively and efficiently querying and mining uncertain data. Existing work in this field either neglects the presence of dependencies or provides only approximate results while applying methods designed for certain data. Other approaches dealing with uncertain data are not able to provide efficient solutions. This part presents query processing approaches that outperform existing solutions of probabilistic similarity ranking. This part finally leads to the application of the introduced techniques to data mining tasks, such as the prominent problem of probabilistic frequent itemset mining.