This episode delves into the potential of artificial intelligence to improve surgical navigation. We examine the feasibility study 'Real-time intraoperative depth estimation in transsphenoidal surgery using deep learning' published in the Journal of Clinical Neuroscience in 2026. The abstract outlines how deep learning algorithms could generate crucial 3D imaging from standard 2D endoscopic feeds, enhancing surgeon orientation during transsphenoidal procedures. This technology aims to overcome the inherent depth perception challenges of endoscopic surgery for various skull base pathologies. The implications for improved patient safety and surgical outcomes are discussed. This podcast is for informational purposes and does not constitute medical advice.