This episode delves into the endoscopic transnasal approach for accessing the pterygopalatine and infratemporal fossae. We review the findings from a case series published in Acta Neurochirurgica in 2026, utilizing the endoscopic modified medial maxillectomy (EMMM) and direct approach to the anterior and lateral maxillary sinus (DALMA) techniques. The discussion highlights the study design, patient population, and critical outcomes, emphasizing the clinical utility of these minimally invasive methods for skull base pathologies. This content is for educational purposes only and does not constitute medical advice. This information is generated by AI and should not be considered a substitute for professional medical guidance.