When patients arrive with acute decompensated heart failure, IV antibiotics are often started “just in case.” But what if that precaution is doing more harm than good? In this episode, we break down new research showing that unnecessary IV antibiotics, packed with extra fluid and surprising amounts of sodium, can worsen outcomes, extend hospital stays, and even increase readmissions. We explore why these effects happen, what the data reveals, and how smarter antimicrobial stewardship can protect vulnerable heart-failure patients. Tune in to learn why sometimes less treatment truly means better care!