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• Research suggests increasing public awareness and opt-out donation systems can boost liver donations, though effectiveness varies by region.
• It seems likely that using extended criteria donors and split liver techniques can expand the donor pool, but outcomes may differ.
• The evidence leans toward machine perfusion and bioengineered livers as promising innovations, though they are still experimental.
• Policy changes, like optimizing allocation, may help, but face ethical debates; living-donor transplants show potential with support.
By Sabin Subedi• Research suggests increasing public awareness and opt-out donation systems can boost liver donations, though effectiveness varies by region.
• It seems likely that using extended criteria donors and split liver techniques can expand the donor pool, but outcomes may differ.
• The evidence leans toward machine perfusion and bioengineered livers as promising innovations, though they are still experimental.
• Policy changes, like optimizing allocation, may help, but face ethical debates; living-donor transplants show potential with support.