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In dieser Episode diskutieren Dr. Sami Ridwan, Dr. Stefan Motov und Dr. Andreas Kramer über die Herausforderungen und Entwicklungen in der Behandlung der Spondylodiszitis. Sie beleuchten die steigende Inzidenz, die Rolle der demografischen Veränderungen und die Unterschiede in den Behandlungskonzepten zwischen verschiedenen Gesundheitssystemen und diskutieren die Vor- und Nachteile konservativer und operativer Therapien.
Takeaways
Literatur
Thavarajasingam SG, Vemulapalli KV, Vishnu K S, Ponniah HS, Vogel AS, Vardanyan R, Neuhoff J, Kramer A, Shiban E, Ringel F, Demetriades AK, Davies BM. Conservative versus early surgical treatment in the management of pyogenic spondylodiscitis: a systematic review and meta-analysis. Sci Rep. 2023 Sep 20;13(1):15647. doi: 10.1038/s41598-023-41381-1. PMID: 37730826; PMCID: PMC10511402.
Bernard L, Dinh A, Ghout I, Simo D, Zeller V, Issartel B, Le Moing V, Belmatoug N, Lesprit P, Bru JP, Therby A, Bouhour D, Dénes E, Debard A, Chirouze C, Fèvre K, Dupon M, Aegerter P, Mulleman D; Duration of Treatment for Spondylodiscitis (DTS) study group. Antibiotic treatment for 6 weeks versus 12 weeks in patients with pyogenic vertebral osteomyelitis: an open-label, non-inferiority, randomised, controlled trial. Lancet. 2015 Mar 7;385(9971):875-82. doi: 10.1016/S0140-6736(14)61233-2. Epub 2014 Nov 5. PMID: 25468170.
Kramer A, Thavarajasingam SG, Neuhoff J, Ponniah HS, Ramsay DSC, Demetriades AK, Davies BM, Shiban E, Ringel F. Epidemiological trends of pyogenic spondylodiscitis in Germany: an EANS Spine Section Study. Sci Rep. 2023 Nov 18;13(1):20225. doi: 10.1038/s41598-023-47341-z. PMID: 37980371; PMCID: PMC10657388.
Kramer A, Thavarajasingam SG, Neuhoff J, Davies BM, Demetriades AK, Shiban E, Ringel F. Variation of practice in the treatment of pyogenic spondylodiscitis: a European Association of Neurosurgical Societies Spine Section study. J Neurosurg Spine. 2024 May 17;41(2):263-272. doi: 10.3171/2024.2.SPINE231202. PMID: 38759237.
Kramer A, Thavarajasingam SG, Neuhoff J, Lange F, Ponniah HS, Lener S, Thomé C, Stengel FC, Fischer G, Hostettler IC, Stienen MN, Jemna M, Gousias K, Nedeljkovic A, Grujicic D, Nedeljkovic Z, Poluga J, Schär RT, Urbanski W, Sousa C, Casimiro CDO, Harmer H, Ladisich B, Matt M, Simon M, Pai D, Doenitz C, Mongardi L, Lofrese G, Buchta M, Grassner L, Trávníček P, Hosszú T, Wissels M, Bamps S, Hamouda W, Panico F, Garbossa D, Barbato M, Barbarisi M, Pantel T, Gempt J, Kasula TS, Desai S, Vitowanu JM, Rovčanin B, Omerhodzic I, Demetriades AK, Davies B, Shiban E, Ringel F. Management of severe pyogenic spinal infections: the 2SICK study by the EANS spine section. Spine J. 2025 May;25(5):876-885. doi: 10.1016/j.spinee.2024.12.018. Epub 2024 Dec 12. PMID: 39672206.
Neuhoff J, Kramer A, Thavarajasingam SG, Sutherland RK, McCaughan H, Joerger AK, Wostrack M, Lyell B, Berkulian O, Ponniah HS, Ramsay DSC, Meyer B, Kandziora F, Shiban E, Davies B, Demetriades AK, Ringel F. Comparing Conservative and Early Surgical Treatments for Pyogenic Spondylodiskitis: An International Propensity Score-Matched Retrospective Outcome Analysis. Neurosurgery. 2024 Oct 17;96(5):1008–22. doi: 10.1227/neu.0000000000003223. Epub ahead of print. PMID: 39471086; PMCID: PMC11970889.
By Dr. Sami Ridwan und Dr. Stefan MotovIn dieser Episode diskutieren Dr. Sami Ridwan, Dr. Stefan Motov und Dr. Andreas Kramer über die Herausforderungen und Entwicklungen in der Behandlung der Spondylodiszitis. Sie beleuchten die steigende Inzidenz, die Rolle der demografischen Veränderungen und die Unterschiede in den Behandlungskonzepten zwischen verschiedenen Gesundheitssystemen und diskutieren die Vor- und Nachteile konservativer und operativer Therapien.
Takeaways
Literatur
Thavarajasingam SG, Vemulapalli KV, Vishnu K S, Ponniah HS, Vogel AS, Vardanyan R, Neuhoff J, Kramer A, Shiban E, Ringel F, Demetriades AK, Davies BM. Conservative versus early surgical treatment in the management of pyogenic spondylodiscitis: a systematic review and meta-analysis. Sci Rep. 2023 Sep 20;13(1):15647. doi: 10.1038/s41598-023-41381-1. PMID: 37730826; PMCID: PMC10511402.
Bernard L, Dinh A, Ghout I, Simo D, Zeller V, Issartel B, Le Moing V, Belmatoug N, Lesprit P, Bru JP, Therby A, Bouhour D, Dénes E, Debard A, Chirouze C, Fèvre K, Dupon M, Aegerter P, Mulleman D; Duration of Treatment for Spondylodiscitis (DTS) study group. Antibiotic treatment for 6 weeks versus 12 weeks in patients with pyogenic vertebral osteomyelitis: an open-label, non-inferiority, randomised, controlled trial. Lancet. 2015 Mar 7;385(9971):875-82. doi: 10.1016/S0140-6736(14)61233-2. Epub 2014 Nov 5. PMID: 25468170.
Kramer A, Thavarajasingam SG, Neuhoff J, Ponniah HS, Ramsay DSC, Demetriades AK, Davies BM, Shiban E, Ringel F. Epidemiological trends of pyogenic spondylodiscitis in Germany: an EANS Spine Section Study. Sci Rep. 2023 Nov 18;13(1):20225. doi: 10.1038/s41598-023-47341-z. PMID: 37980371; PMCID: PMC10657388.
Kramer A, Thavarajasingam SG, Neuhoff J, Davies BM, Demetriades AK, Shiban E, Ringel F. Variation of practice in the treatment of pyogenic spondylodiscitis: a European Association of Neurosurgical Societies Spine Section study. J Neurosurg Spine. 2024 May 17;41(2):263-272. doi: 10.3171/2024.2.SPINE231202. PMID: 38759237.
Kramer A, Thavarajasingam SG, Neuhoff J, Lange F, Ponniah HS, Lener S, Thomé C, Stengel FC, Fischer G, Hostettler IC, Stienen MN, Jemna M, Gousias K, Nedeljkovic A, Grujicic D, Nedeljkovic Z, Poluga J, Schär RT, Urbanski W, Sousa C, Casimiro CDO, Harmer H, Ladisich B, Matt M, Simon M, Pai D, Doenitz C, Mongardi L, Lofrese G, Buchta M, Grassner L, Trávníček P, Hosszú T, Wissels M, Bamps S, Hamouda W, Panico F, Garbossa D, Barbato M, Barbarisi M, Pantel T, Gempt J, Kasula TS, Desai S, Vitowanu JM, Rovčanin B, Omerhodzic I, Demetriades AK, Davies B, Shiban E, Ringel F. Management of severe pyogenic spinal infections: the 2SICK study by the EANS spine section. Spine J. 2025 May;25(5):876-885. doi: 10.1016/j.spinee.2024.12.018. Epub 2024 Dec 12. PMID: 39672206.
Neuhoff J, Kramer A, Thavarajasingam SG, Sutherland RK, McCaughan H, Joerger AK, Wostrack M, Lyell B, Berkulian O, Ponniah HS, Ramsay DSC, Meyer B, Kandziora F, Shiban E, Davies B, Demetriades AK, Ringel F. Comparing Conservative and Early Surgical Treatments for Pyogenic Spondylodiskitis: An International Propensity Score-Matched Retrospective Outcome Analysis. Neurosurgery. 2024 Oct 17;96(5):1008–22. doi: 10.1227/neu.0000000000003223. Epub ahead of print. PMID: 39471086; PMCID: PMC11970889.