A diagnosis of stage 4 colorectal cancer means that the disease has metastasized. In other words, cancer cells have spread beyond the colon or rectum to distant organs, such as the liver, lungs, or peritoneum. Colorectal cancer stage 4 is considered the most advanced and aggressive form of the disease. According to the World Health Organization, colorectal cancer ranks as the third most common cancer worldwide, with over 1.9 million new cases and more than 930,000 deaths reported annually. Approximately 20% of patients are diagnosed at stage 4, when the cancer has already spread. The 5-year survival rate for stage 4 colorectal cancer is estimated at around 13%. However, this figure may vary depending on the patient's overall health, extent of metastasis, and the treatments used.

Patients and their families often associate the term "late-stage" with hopelessness. However, colorectal cancer stage 4 treatment has evolved rapidly in recent years. Traditional approaches like chemotherapy are being complemented and, in some cases, outperformed by innovative, highly targeted therapies. While this diagnosis is undoubtedly serious, it is not without options. Thanks to advanced treatment strategies tailored to the patient's specific case, many individuals with metastatic colorectal cancer are now living longer, more fulfilling lives.

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