Joint pain ranks among the most widespread musculoskeletal conditions in Europe, currently affecting over 57 million adults in Western Europe, which is more than a 50% increase since 1990. Nearly 43% of these individuals are under the age of 65, which dispels the misconception that joint disorders only affect the elderly. In addition, knee osteoarthritis, which is one of the most common sources of joint pain, accounts for approximately 1.28% of all years lived with disability in Europe. Traditional interventions such as physical therapy, non‑steroidal anti‑inflammatory medications, and surgery often alleviate symptoms but rarely address underlying joint degeneration. This gap in treatment efficacy has led to a growing interest in regenerative therapies.

Stem cells for joint pain therapy have emerged as a promising approach, utilizing the body's own regenerative capacity to reduce inflammation, support repair, and potentially regenerate cartilage. By directly targeting tissue degeneration, it holds the potential to offer more sustained pain relief and delay, or even eliminate, the need for invasive procedures.

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