The fever persists but does that mean treatment is failing? Not necessarily. In this episode we unpack why ongoing fevers do not automatically signal the need to escalate antibiotics. Instead, smart stewardship focuses on the bigger picture including hemodynamic stability, improving organ function, and microbiologic data that reveal the true course of infection. You will learn how to interpret persistent fevers, avoid unnecessary drug toxicity, and make informed decisions that fight antibiotic resistance all without overreacting to the thermometer.