In this episode, we explore an innovative approach to managing Parkinson’s symptoms in patients with swallowing difficulties. Hear the story of an 85-year-old man with Lewy body dementia who experienced rapid symptom relief through sublingual administration of crushed levodopa/carbidopa—a practical alternative when traditional oral or rectal routes aren’t feasible. We discuss the challenges of medication delivery in dysphagic patients, the potential benefits and limitations of sublingual dosing, and the need for further research to optimize this promising method.