The New York Giants (1-4) will travel to Highmark Stadium in Orchard Park, New York to take on the Buffalo Bills (3-2) on Sunday Night Football in Week 6 of the NFL season. The Bills are the heavy favorites in this matchup, as they are currently favored by 15.5 points. The Bills have one of the most explosive offenses in the NFL, led by quarterback Josh Allen. Allen has thrown for 1,225 yards and 11 touchdowns in the first five games of the season. He is also a dangerous runner, with 237 rushing yards and three touchdowns.

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