42.241

regardless of something

something-less means without that something

so regardless means without regard to

without regard to

AS IN regardless of how serious

regardless of costs

as goes the saying - less is more

but in reality – more is more

and less is always less

42.242

regardless of how effective or ineffective

regardless of how frequent or infrequent

regardless of how successful or unsuccessful

regardless of how legal or illegal

regardless of how proper or improper

regardless of how colorful or colorless

REGARDLESS

42.243

without regard to how effective or ineffective

effective or dysfunctional

regardless of how efficient or inefficient

efficient or incapable

regardless of if it is valid or invalid

valid or absurd

42.244

regardless of it being impressive or unimpressive

impressive or despicable

regardless of how influential or non-influential

influential or insignificant

of how potent or impotent

potent or abortive

42.245

never mind it being productive or unproductive

productive or abortive

irrespective of how practical or impractical

practical or idealistic

have no idea if it was proper or improper

proper or inappropriate

it is immaterial if she was competent or incompetent

competent or an ignoramus

complete ignoramus