The backstory of Peia and Bruno Mannheim is explored, providing insight into their love story and motivations. As Lois's cancer diagnosis takes center stage, Jon and Jordan grapple with their mother's condition and the harsh reality of her end-of-life documents. Meanwhile, Sarah navigates her father's new relationship with Chrissy. John Henry faces the challenges of being an overprotective father when his daughter Natalie starts dating Matteo.