SwineCast 1069 Show Notes: Keith Wilson, DVM, senior professional service veterinarian at Boehringer Ingelheim, shares how custom vaccines are created and what pork producers should expect when custom vaccines are needed on their operations. "Adjuvants are the biggest variable that impact vaccine performance," said Dr. Wilson. "Nearly everything else within a killed vaccine is fixed, such as the antigens and routes of administration." Unlike commercial killed vaccines, custom-made vaccines give producers and veterinarians the option to select an adjuvant that can help solve their herd’s health challenges. Determining the optimal adjuvant to use in a vaccine is critical, because different adjuvants have different abilities when triggering immune responses.