Recharge Podcast

Switching Hair Loss Drugs


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It occurs whether or not a patient is taking any sort of medication or remedy for hair loss. 

 But when transitioning from Finasteride to Minoxidil or vice versa, it certainly is possible to experience some degree of shedding. 

 This is because they work differently through different mechanisms. 

 Finasteride primarily inhibits the hormone responsible for hair loss, miniaturization, thinness, brittleness, and all the negative things that go along with male pattern hair loss and also in females as well, to some degree, and that is DHT. 

 Minoxidil works through a different mechanism relative to Finasteride. 

 Although there is some overlap and evidence in smaller studies about the hormonal impacts of Minoxidil, it is not a potent DHT blocker.

 Minoxidil, which is an old blood pressure medication, works by stimulating hair growth. The theory is that it increases blood flow through the follicle, which increases nutrient delivery to the follicles themselves and can enhance hair growth. The mechanism is more complex, but I'll save that for another video.

 Obviously, hair loss is very individual, depending on genetics. Lifestyle, hormones, stress, illness, a variety of other things. 

 Stopping Finasteride can lead to a temporary increase in hair shedding as the body adjusts to the absence of the DHT-blocking effects at the levels of hair follicles. 

 Next is the time it takes to regrow hair, which is really variable and depends on genetic factors, as I alluded to before, and a variety of other things, including environment, health, and lifestyle. 

 One of the things that people fail to understand or recognize is that there are a variety of environmental toxins that can impact not only general health but also hair loss and hair regrowth. 

 It takes a few months for hair to go through its normal life cycles, and therefore, it will take a few months in general for most to see any particular change, whether or not they're using Minoxidil, Finasteride, topical, or a combination of any of the previous. 

 During this transition period, the hair that's lost from stopping Finasteride might not be immediately replaced by new growth from that triggered by Minoxidil. 

 It's important to have some realistic expectations to understand that this process is gradual. It's going to take time. I get many concerned messages that "my hair is not all back after two weeks." Being patient and understanding time are critical factors.

 

 

Oral Minoxidil obviously is more systemic and, based on absorption and the mechanism of action, should work on viable follicles wherever they are, which is in part by the explanation of side effects by patients who are taking Minoxidil may note hair growth in other places that maybe they don't prefer like the back, sides of the face, the temples, areas like that. 

 

So, it's crucial to understand that the changes and the process of hair loss are individual and depend on many factors. This video is just a mechanism and a method to share information and education. 

 

So take care. Be well. Subscribe for more content like this.

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Recharge PodcastBy Mitchel Schwindt, M.D. | author | online courses | coaching | consulting

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