This article "Systematic profiling reveals betaine as an exercise mimetic for geroprotection" is published in Cell.

Author:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Lingling Geng

Journal:Cell

Year:2025

Podcast type:Short

The authors are ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 

Lingling Geng, 1,18 Jiale Ping, 3,5,18 Ruochen Wu, 2,5,18 Haoteng Yan, 1,18 Hui Zhang, 7,18 Yuan Zhuang, 8,18 Taixin Ning, 1,18

Jun Wang, 5,6,18 Chuqian Liang, 2,5,18 Jiachen Zhang, 1 Qingqing Chu, 7 Jing Zhang, 1 Yifan Wen, 2,5 Yaobin Jing, 9

Shuhui Sun, 7 Qin Qiao, 3 Qian Zhao, 1 Qianzhao Ji, 2,4 Shuai Ma, 2,4,5,17,5 Yusheng Cai, 2,4 Yandong Zheng, 1,2,5 Zhiran Zou, 2,5

Zhiqing Diao, 2,5 Mingheng Li, 2,5 Hao Zhang, 2,5 Jianli Hu, 3,5 Liangzheng Fu, 2,5 Wang Kang, 3,5 Ruijun Bai, 2 Hongkai Zhao, 2,5

Sheng Zhang, 2,5 Yingjie Ding, 3,5 Jinghui Lei, 1 Wei Wang, 2,5 Yun Ji, 2,5 Bo Gou, 2,5 Guoqiang Sun, 2,5 Jian Yin, 2,5

Pengze Yan, 2,5 Hao Li, 3,5 Zehua Wang, 2,5 Shikun Ma, 2 Zunpeng Liu, 2,5 Hezhen Shan, 2 Qiaoran Wang, 3,5 Tianling Cao, 2,5

Shanshan Yang, 1 Cui Wang, 3,5 Ping Yang, 2,5 Yanling Fan, 3 Yanxia Ye, 2,4 Jinghao Hu, 1 Mengmeng Jiang, 2,4 Ye Wang, 12

Kan Liu, 12 Yujing Li, 2,5 Yuanxiang Li, 2,5 Jingyi Li, 2,4,5,17 Weimin Ci, 12,19 Zi-Bing Jin, 13,17,19 Xiaobing Fu, 14,19 Xu Zhang, 12,19

Guoguang Zhao, 11,19 Juan Carlos Izpisua Belmonte, 10,16,19 Si Wang, 1,17, * Moshi Song, 2,4,5,15,17, * Weiqi Zhang, 3,5,17, *

Jing Qu, 2,4,5,7,15,17, * and Guang-Hui Liu 1,2,4,5,15,17,20,

Affiliations:

1 Advanced Innovation Center for Human Brain Protection, National Clinical Research Center for Geriatric Disorders, Aging Translational

Medicine Center, Beijing Municipal Geriatric Medical Research Center, Beijing Key Laboratory of Environment and Aging, Xuanwu Hospital

Capital Medical University, Beijing 100053, China

2 State Key Laboratory of Organ Regeneration and Reconstruction, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China

3 China National Center for Bioinformation, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China

4 Beijing Institute for Stem Cell and Regenerative Medicine, Beijing 100101, China

5 University of Chinese Academy of Sciences, Beijing 100049, China

6 CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101,

China

7 Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China

8 Department of Blood Transfusion, First Medical Center of Chinese PLA General Hospital, Beijing 100853, China

9 International Center for Aging and Cancer, Hainan Academy of Medical Sciences, Hainan Medical University, Haikou 571199, Hainan, China

10 Altos Labs San Diego Institute of Science, San Diego, CA, USA

11 Department of Neurosurgery, National Medical Center for Neurological Diseases, Beijing Municipal Geriatric Medical Research Center,

Xuanwu Hospital Capital Medical University, Beijing 100053, China

12 Department of Urology, Chinese PLA General Hospital, PLA Medical School, Beijing 100853, China

13 Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology

& Visual Science Key Laboratory, Beijing 100730, China

14 Tissue Repair and Regeneration Research Center, Medical Innovation Department, PLA General Hospital and Medical College, Beijing

100842, China

15 Human Organ Physiopathology Emulation System, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China

16 Salk Institute for Biological Studies, La Jolla, CA 92037, USA

17 Aging Biomarker Consortium (ABC), Beijing 100101, China

18 These authors contributed equally

19 Senior author

20 Lead contact