In this interview with Dr. Jo Shapiro, Associate Professor of Otolaryngology Head and Neck Surgery at Harvard Medical School and founder of the Brigham and Women’s Center for Professionalism and Peer support, we discuss what hospitals can do to establish similar programs at their own institutions. Dr. Shapiro shares insights from her experience of building the Center’s program and discusses the evidence behind its design, highlighting those elements essential to developing a program that can make a tangible impact in reducing clinician stress and enhancing well-being.