Pastor Mike's sermon emphasizes the importance of prayer, drawing from two passages in Luke (chapters 11 and 18). Key points include building a 'theology of prayer' and adopting various 'postures of prayer' such as intimacy, dependence, persistence, shamelessness, childlikeness, perseverance, relentlessness, expectancy, and watchfulness. Jesus' teachings and parables serve as a guide for how to pray effectively. The congregation is encouraged to actively engage in prayer, trusting in God's timing and wisdom, while also praying for specific needs and broader missional opportunities.