The sermon focuses on the importance of prayer in the life of a believer, emphasizing that prayer is not just a religious obligation but a vital connection to God. It highlights the significance of prayer as a means of developing intimacy with God, understanding His heart, and aligning our lives with His purposes. The speaker debunks common myths about prayer, such as the need for perfect words or settings, and encourages believers to embrace their identity as royalty in Christ, with servanthood as their assignment and intimacy with God as their life source.