The sermon focuses on the importance and simplicity of prayer, emphasizing that prayer should be as natural as talking to a friend. It encourages believers to engage in prayer and fasting as a means to draw closer to God, especially as the church prepares for a significant spiritual movement in 2025. The message highlights the need to spend time with God to become more like Him, and it introduces a model of prayer based on the Lord's Prayer, which includes worship, declaration, purification, and asking for strength.