The Amazon rainforest is under increasing pressure from climate change, deforestation, extractive industries like mining, and a range of human-induced factors. This episode explores the public health impacts of human-induced pressures on the Amazon, including an increased risk of yellow fever outbreaks. With Dr Anice Sallum, medical epidemiology and entomology professor at Sao Paolo University’s School of Public Health, and Dr Amy Vittor, Assistant Professor in Infectious Diseases and Global Medicine at the University of Florida.