David Deutsch's The Beginning of Infinity argues that knowledge is not simply derived from experience, but rather from the process of conjecture and criticism. The text examines how scientific knowledge is generated through seeking good explanations, which are explanations that are hard to vary. Deutsch contrasts this approach to knowledge with the idea that knowledge is justified by some source or criterion, which he critiques as justificationism. The book further explores concepts such as fallibilism, the nature of the multiverse, and the role of human creativity in the development of knowledge. By examining various examples ranging from the explanation of seasons to the workings of a domino computer, Deutsch emphasizes the importance of seeking universal explanations and challenging parochial perspectives. The text culminates in a discussion of the future of creativity, arguing that the power of human imagination is unlimited, and that humanity's ability to create knowledge can continue indefinitely.