Slice of Science

The Bittersweet Effects of St John's Wort


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SoS Christmas eddition, we're talking worts from Jesus's right hand man St John the Baptist!

Tune in to hear all the good AND bad sides of a powerful herb called St John's wort.

Sources

  • Davidson, J. R., et al, 2002. Effect of Hypericum perforatum (St John's wort) in major depressive disorder: a randomized controlled trial, Jama, https://jamanetwork.com/journals/jama/fullarticle/194814
  • Di Carlo, G., et al, 2001. St John's wort: Prozac from the plant kingdom, Trends in Pharmacological Sciences, https://www.semanticscholar.org/paper/St-John's-wort%3A-Prozac-from-the-plant-kingdom.-Carlo-Borrelli/fe55e78497080d8ec313467db46cec54960b0605
  • Linde, K., et al, 2005. St John's Wort for depression, Cochrane Database of Systematic Reviews,https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD000448.pub2/full
  • Mills, E., et al, 2004. Interaction of St John's wort with conventional drugs: systematic review of clinical trials, BMJ, https://www.bmj.com/content/bmj/329/7456/27.full.pdf
  • Nicolussi, S., et al, 2020. Clinical relevance of St. John's wort drug interactions revisited, British Journal of Pharmacology, https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14936
  • Vorbach, E. U., et al, 1997. Efficacy and tolerability of St. John's wort extract LI 160 versus imipramine in patients with severe depressive episodes according to ICD-10, Pharmacopsychiatry, https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-2007-979524
  • https://weeds.org.au/profiles/st-johns-wort/
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Slice of ScienceBy Michelle Sims