In this episode of We're Overdosed, scientist Barry I. Gold takes us through the history of opium, beginning with its origins and tracing the development of morphine and the subsequent synthesis of opioids, which ultimately led to the creation of the global pharmaceutical industry. Barry offers a scientific perspective on the role Federal legislation could play in regulating prescription opioids, suggesting that better control of these substances is essential in addressing the ongoing opioid crisis. He also explores the challenges posed by the illicit drug trade, discussing how the United States could take a leadership role in combating the international flow of illegal substances that continue to contribute to the epidemic of overdose deaths.