The 24th episode of the OFID podcast, hosted by OFID Editor Paul Sax, MD, explores the motivations and histories of two brothers who both followed their father’s footsteps into medicine, but then forayed into infectious diseases and now jointly own a private practice in Memphis, TN. Michael Threlkeld, MD, and Steven Threlkeld, MD, reveal what drew them both to infectious diseases, what the caseload looks like in the southeastern U.S., and the importance of community medicine rotations in training well-rounded clinicians.