Let’s delve into the clinical applications of in silico medicine! Our guest for this episode is Dr. Elisa Rauseo, cardiologist and Clinical Research Fellow in Cardiovascular Digital Twins at the Queen Mary University of London. Together, we will discuss the applications of AI and machine learning in cardiology and also how ready medical doctors are to apply in silico tools in their practice.

Musculoskeletal applications are among the most advanced frontiers of in silico medicine. In our first episode of 2025, we sit down with a true pioneer in the field—Prof. Marco Viceconti.

From the early days, when only a handful of visionaries foresaw a future where medicine was driven by data and computational models, to the present, Marco has been a driving force in this revolution.

His contributions are remarkable: he founded and directed the Medical Technology Lab at the Istituto Ortopedico Rizzoli, established and led the Insigneo Institute for In Silico Medicine, and served as the first Executive Director of VPHi.

Join us as we explore the evolution of in silico medicine through the insights of one of its most influential figures.

In silico medicine is transforming healthcare, and some of its most groundbreaking applications are happening in cardiology. In our final episode of 2024, we explore how this innovative technology is reshaping the future of heart health.

Joining us is Mariano Vazquez, CTO and CSO of ELEM Biotech—a spinoff of the Barcelona Supercomputing Center (BSC)—where he also leads cutting-edge research.

In this episode, we will discuss about social implications and trust in in silico medicine with our guest Zita van Horenbeeck, social scientist at the Virtual Physiological Human Institute and PhD student at the Life Sciences and Society Lab of KU Leuven.

In silico medicine, as a breakthrough in technology and healthcare, carries a series of ethical issues, including managing personal health data, the technological divide, and the doctor-patient relationship.


To explore this topic, we interviewed Michele Barbier, an independent ethics expert for the European Commission and EU project coordinator at INRIA working on digital twins. Her insights offer a closer look at this transformative field's challenges and promises.

Without data, in silico medicine wouldn't even be possible. In this episode we will explore how data, especially medical data, needs to be managed to make in silico medicine a reality.

Our guest for this episode is Elisabetta Biasin, doctoral researcher at the Centre for IT and IP Law at KU Leuven.

Do you know how long it takes for a drug to reach the pharmacy?

Drug development, testing, and approval take 10 to 15 years and cost millions of euros. Most of this time and money go into clinical trials, which are essential for proving the drug's safety and effectiveness.

Clinical trials are crucial, but can we make this process faster, cheaper, and safer for both animals and humans? The short answer is yes. For the longer answer, we turn to the guest of this episode, Francesco Pappalardo, Professor of Computer Science at the University of Catania.

As an in silico medicine tool, Artificial Intelligence is revolutionising healthcare. When did it start? And how can AI contribute to improving and making doctors' work more efficient worldwide? We asked such questions to Leonardo Castorina, PhD student in Biomedical AI at the University of Edinburgh, specialising in AI-driven protein design and immune system research.

Don't miss out on our animated video series, Code & Cure: Understanding in silico medicine. Here's the link to the third episode: https://youtu.be/xctWc8n7eC8

What is a computer model? How can we build one? How can they be used to improve healthcare? We asked all such questions to Himanshu Kaul, Royal Academy of Engineering Research Fellow and Principal Investigator at the Laboratory for Multiscale Emergent Bioengineering at the University of Leicester.

Don't miss our animated video series Code & Cure: Understanding in silico medicine. Here's the link to the second episode of the series: https://youtu.be/gAeHWcKxDZI

In silico medicine is the future of healthcare. But what is it really? And what can it do for us? We interviewed Liesbet Geris, professor of Biomechanics and Computational Tissue Engineering at the University of Liege and KU Leuven. She’s also the executive director of the Virtual Physiological Human Institute.

Don't miss our video series Code & Cure: Understanding in silico medicine. Here's the link to the first episode: https://youtu.be/5YjjzHlHsok