Microsoft CEO Satya Nadella predicts the demise of traditional SaaS applications, arguing that AI agents will directly interact with databases, eliminating the need for separate user interfaces. This shift necessitates a reimagining of software development, focusing on AI-native architectures, robust data infrastructure, and agent-driven workflows. Startups must adapt by developing AI agents, enhancing data layers, and focusing on user experience simplification to thrive in this new "agent era." The opportunity lies in building platforms and solutions that leverage AI agents for enhanced efficiency and user interaction across various industries.

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