In this episode, we discuss the FAST trial that compared a new and rapid antibiotic susceptibility test to standard practice. We discuss the rationale, trial design, the DOOR outcome framework and its analytical approach, and the limitations.

In this episode, we discuss the FAST trial that compared a new and rapid antibiotic susceptibility test to standard practice. We discuss the rationale, trial design, the DOOR outcome framework and its analytical approach, and the limitations.

The FAST trial: Rapid vs. Standard AST

Our take on the latest critical care evidence with deep insights on methods, interpretation, clinical relevance and so much more!CRITKNOW is co-hosted by Bharath Kumar Tirupakuzhi Vijayaraghavan and Ramesh Venkataraman.Bharath is a mid-career clinician–researcher with a primary focus on improving outcomes from critical illness in patients in low- and middle-income countries (LMICs). He is also deeply passionate about teaching evidence-based medicine and helping clinicians interpret and apply emerging evidence in patient care. You can learn more about his work here: <a rel="noopener noreferrer nofollow" href="https://www.researchgate.net/profile/Bharath-Kumar-Tirupakuzhi-Vijayaraghavan?ev=hdr_xprf" target="_blank">https://www.researchgate.net/profile/Bharath-Kumar-Tirupakuzhi-Vijayaraghavan?ev=hdr_xprf</a>Ramesh is American Board–certified in Internal Medicine, Critical Care Medicine, and Neurocritical Care. He is also a senior researcher with a special interest in acute kidney injury and renal replacement therapy. A highly respected teacher and educator, he has a unique ability to integrate emerging evidence into bedside clinical practice. You can learn more about his work here: <a rel="noopener noreferrer nofollow" href="https://icuconsultants.com/dr-ramesh-venkataraman/" target="_blank">https://icuconsultants.com/dr-ramesh-venkataraman/</a>Bharath and Ramesh are both Senior Consultants in the Department of Critical Care Medicine at Apollo Hospitals, Chennai and affiliated with Chennai Critical Care Consultants Private Limited, an academic critical care group practice (<a rel="noopener noreferrer nofollow" href="https://icuconsultants.com/" target="_blank">https://icuconsultants.com/</a>). Bharath is also affiliated with the University of Edinburgh as a Clinical Research Fellow (<a rel="noopener noreferrer nofollow" href="https://inflammation-research.ed.ac.uk/research/research-groups/dr-bharath-kumar" target="_blank">https://inflammation-research.ed.ac.uk/research/research-groups/dr-bharath-kumar</a>)Views expressed are personal.

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Our take on the latest critical care evidence with deep insights on methods, interpretation, clinical relevance and so much more! CRITKNOW is co-hosted by Bharath Kumar Tirupakuzhi Vijayaraghavan and Ramesh Venkataraman. Bharath is a mid-career clinician–researcher with a primary focus on improving outcomes from critical illness in patients in low- and middle-income countries (LMICs). He is also deeply passionate about teaching evidence-based medicine and helping clinicians interpret and apply emerging evidence in patient care. You can learn more about his work here: https://www.researchgate.net/profile/Bharath-Kumar-Tirupakuzhi-Vijayaraghavan?ev=hdr_xprf Ramesh is American Board–certified in Internal Medicine, Critical Care Medicine, and Neurocritical Care. He is also a senior researcher with a special interest in acute kidney injury and renal replacement therapy. A highly respected teacher and educator, he has a unique ability to integrate emerging evidence into bedside clinical practice. You can learn more about his work here: https://icuconsultants.com/dr-ramesh-venkataraman/ Bharath and Ramesh are both Senior Consultants in the Department of Critical Care Medicine at Apollo Hospitals, Chennai and affiliated with Chennai Critical Care Consultants Private Limited, an academic critical care group practice (https://icuconsultants.com/). Bharath is also affiliated with the University of Edinburgh as a Clinical Research Fellow (https://inflammation-research.ed.ac.uk/research/research-groups/dr-bharath-kumar) Views expressed are personal.

Our take on the latest critical care evidence with deep insights on methods, interpretation, clinical relevance and so much more!CRITKNOW is co-hosted by Bharath Kumar Tirupakuzhi Vijayaraghavan and Ramesh Venkataraman.Bharath is a mid-career clinician–researcher with a primary focus on improving outcomes from critical illness in patients in low- and middle-income countries (LMICs). He is also deeply passionate about teaching evidence-based medicine and helping clinicians interpret and apply emerging evidence in patient care. You can learn more about his work here: <a href="https://www.researchgate.net/profile/Bharath-Kumar-Tirupakuzhi-Vijayaraghavan?ev=hdr_xprf" rel="noopener noreferrer">https://www.researchgate.net/profile/Bharath-Kumar-Tirupakuzhi-Vijayaraghavan?ev=hdr_xprf</a>Ramesh is American Board–certified in Internal Medicine, Critical Care Medicine, and Neurocritical Care. He is also a senior researcher with a special interest in acute kidney injury and renal replacement therapy. A highly respected teacher and educator, he has a unique ability to integrate emerging evidence into bedside clinical practice. You can learn more about his work here: <a href="https://icuconsultants.com/dr-ramesh-venkataraman/" rel="noopener noreferrer">https://icuconsultants.com/dr-ramesh-venkataraman/</a>Bharath and Ramesh are both Senior Consultants in the Department of Critical Care Medicine at Apollo Hospitals, Chennai and affiliated with Chennai Critical Care Consultants Private Limited, an academic critical care group practice (<a href="https://icuconsultants.com/" rel="noopener noreferrer">https://icuconsultants.com/</a>). Bharath is also affiliated with the University of Edinburgh as a Clinical Research Fellow (<a href="https://inflammation-research.ed.ac.uk/research/research-groups/dr-bharath-kumar" rel="noopener noreferrer">https://inflammation-research.ed.ac.uk/research/research-groups/dr-bharath-kumar</a>)Views expressed are personal.

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The FAST trial: Rapid vs. Standard AST

The FAST trial: Rapid vs. Standard AST