In a special departure from the usual format, Randy Appell sits down with Dr. Mark Mattson—a trailblazing neuroscientist, 20-year veteran of the National Institutes of Health, and one of the leading minds behind the science of intermittent fasting. His groundbreaking research not only reshaped how we think about nutrition and health but also sparked a movement that continues to captivate scientists and the Internet alike.

Why would a world-renowned researcher join a high school–themed podcast? The answer might surprise you. Together, Randy and Dr. Mattson explore the origins of intermittent fasting, the personal journey that fueled his discoveries, and the science behind why it works. But the conversation doesn't stop there—they also dive into the deeper question: is there a biological reason why high school truly matters in shaping who we are?

From cutting-edge dietary insights to thought-provoking reflections on memory, identity, and health, this episode offers more than just science—it's a lively and unexpected dialogue that pushes the boundaries of what "High School Matters" can be.

Follow @HSMattersPodcast