Dr. Charley Cox was one of the early contributors to adhesive dental research, specifically in the field of histology. During the development of adhesive dentistry, Dr. Cox studied long-term pulp health in non-human primates, identified immune responses that confirmed Martin Brannstrom’s hydrodynamic theory of pain and connected internationally with adhesive dental researchers like Takao Fusayama, Stefan Paul and Sema Belli. 

Dr. Cox’s dental research contributions are to this day still largely unincorporated into adhesive dental applications. In creating his Six Lessons Approach to Biomimetic Restorative Dentistry, Dr. David Alleman found Dr. Cox’s research to be instrumental in answering questions about preserving pulp health and preventing reinfection. 

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