In this episode of the Innovation Mindset Podcast, hosted by Mark McNees, we are joined by Sai Devulapalli, team lead of the FSU IGEM project. The team has been working on a solution for Trimethylaminuria (TMAU), also known as fish odor syndrome. TMAU is a rare disorder where an individual's sweat and urine exude a strong fish odor caused by an over-accumulation of Trimethylamine. The team is developing a probiotic enzyme to counter this issue. Despite the condition's rarity and the ongoing lab process, Sai is hopeful that their therapeutic solution could eventually help those suffering from the syndrome, giving them a much-needed intervention for managing their symptoms. Engage in the conversation exploring this innovative medical solution, the intricacies of the issue, and the possible impacts on the TMAU community.

Social MediaWebsite: https://2023.igem.wiki/fsu/Instagram: @fsuigem

FSU iGEM 2023 Team MembersElizabeth Moore (Team Lead), Sai Devulapalli (Associate Team Lead & Entrepneurship Lead)Graeme Pugsley (Build Lead), Eva Lobaton (Design Lead), Vicenzo DeVito (Modeling Lead), Prerna Ravinder (Software Lead), Christian Suastegui (Co- Human Practices Lead), Colton Keib (Co-Human Practices Lead)Remaining Team Members: John Amos, Hanna Yilma-Rodriguez, Talia Valentine, Sonali Shakya, Jolene JonesPrincipal Investigators: Dr. Cesar Rodriguez and Mr. David Montez

00:05 Introduction to the Innovation Mindset Podcast00:37 Understanding T. M. A. U. (Fish Odor Syndrome)01:07 The Impact of T. M. A. U. on Individuals02:41 The Science Behind T. M. A. U.05:43 Developing a Probiotic Solution for T. M. A. U.09:18 Challenges and Progress in Lab Testing16:05 The Path to Market: FDA Compliance and Approval25:29 The Future of the Project and Call for Support28:57 Conclusion and Final Remarks

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